Linker Information
General Information of This Linker
| Linker ID |
LIN0HTGJR
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| Linker Name |
CN116137818A-AbT-EXP9-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H36N6O13S
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| Isosmiles |
O=C(O)OCC1=C(S(=O)(O)=O)C=C(NC([C@H](CCCNC(N)=O)NC(C2(C(NCCOCCN3C(C=CC3=O)=O)=O)CCC2)=O)=O)C=C1
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| InChI |
InChI=1S/C28H36N6O13S/c29-26(40)31-10-1-3-19(23(37)32-18-5-4-17(16-47-27(41)42)20(15-18)48(43,44)45)33-25(39)28(8-2-9-28)24(38)30-11-13-46-14-12-34-21(35)6-7-22(34)36/h4-7,15,19H,1-3,8-14,16H2,(H,30,38)(H,32,37)(H,33,39)(H,41,42)(H3,29,31,40)(H,43,44,45)/t19-/m0/s1
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| InChIKey |
IWFFWCSOTZQYTD-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
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696.692
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Polar area
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289.93
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Complexity
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1487.027215
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xlogp Value
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-0.7722
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Heavy Count
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48
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Rot Bonds
|
18
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Hbond acc
|
11
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker