Linker Information
General Information of This Linker
| Linker ID |
LIN0HQFSW
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| Linker Name |
Linker of ADC2-57
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H51N9O15
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCNC(CNC(/C=C\C(O)=O)=O)=O)=O)CCC(NC[C@@H](O1)[C@@H](O)[C@@H](O)[C@@H]1CC(N)=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(O)=O)=O)C
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| InChI |
InChI=1S/C32H51N9O15/c1-15(2)26(30(52)40-17(31(53)54)4-3-10-36-32(34)55)41-29(51)16(39-23(45)9-11-35-24(46)14-38-22(44)7-8-25(47)48)5-6-21(43)37-13-19-28(50)27(49)18(56-19)12-20(33)42/h7-8,15-19,26-28,49-50H,3-6,9-14H2,1-2H3,(H2,33,42)(H,35,46)(H,37,43)(H,38,44)(H,39,45)(H,40,52)(H,41,51)(H,47,48)(H,53,54)(H3,34,36,55)/b8-7-/t16-,17-,18-,19+,26-,27-,28+/m0/s1
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| InChIKey |
WCGCAIRUSOOMSJ-JERKFRPRSA-N
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| Pharmaceutical Properties |
Molecule Weight
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801.808
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Polar area
|
397.1
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Complexity
|
1396.673935
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xlogp Value
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-5.8458
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Heavy Count
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56
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Rot Bonds
|
25
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Hbond acc
|
13
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Hbond Donor
|
13
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Each Antibody-drug Conjugate Related to This Linker