General Information of This Linker
Linker ID
LIN0HPYGT
Linker Name
CN119630431A-ADC-64-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C34H33N5O8S2
Isosmiles
O=C(O)CNC([C@@H](NC(CNC(CNC(CCN(C(C(SC1=CC=CC=C1)=C2SC3=CC=CC=C3)=O)C2=O)=O)=O)=O)CC4=CC=CC=C4)=O
InChI
InChI=1S/C34H33N5O8S2/c40-26(35-19-27(41)36-20-28(42)38-25(32(45)37-21-29(43)44)18-22-10-4-1-5-11-22)16-17-39-33(46)30(48-23-12-6-2-7-13-23)31(34(39)47)49-24-14-8-3-9-15-24/h1-15,25H,16-21H2,(H,35,40)(H,36,41)(H,37,45)(H,38,42)(H,43,44)/t25-/m0/s1
InChIKey
YZZSLZJZXDXCDS-VWLOTQADSA-N
Pharmaceutical Properties
Molecule Weight
703.799
Polar area
191.08
Complexity
1593.997188
xlogp Value
1.7022
Heavy Count
49
Rot Bonds
17
Hbond acc
9
Hbond Donor
5
Each Antibody-drug Conjugate Related to This Linker