Linker Information
General Information of This Linker
| Linker ID |
LIN0HLMAJ
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| Linker Name |
CN112604004B-SCT-200-M-1-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H44N6O9
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| Isosmiles |
O=C(OCC1=CC=C(C=C1)NC(C(NC(C(NC(CCCCCCCN2C(C=CC2=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)O
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| InChI |
InChI=1S/C31H44N6O9/c1-20(2)27(36-24(38)10-6-4-3-5-7-18-37-25(39)15-16-26(37)40)29(42)35-23(9-8-17-33-30(32)43)28(41)34-22-13-11-21(12-14-22)19-46-31(44)45/h11-16,20,23,27H,3-10,17-19H2,1-2H3,(H,34,41)(H,35,42)(H,36,38)(H,44,45)(H3,32,33,43)
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| InChIKey |
GRXUWMXKENATRO-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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644.726
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Polar area
|
226.33
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Complexity
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1190.99279
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xlogp Value
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2.1594
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Heavy Count
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46
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Rot Bonds
|
20
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker