Linker Information
General Information of This Linker
| Linker ID |
LIN0HKQZS
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|---|---|---|---|---|---|---|
| Linker Name |
Maleimide-thiol linker
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| Linker Type |
Flexible reactive (thiol) linker
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C23H30N4O6
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| Isosmiles |
O=C(CCCCN1C(=O)C=CC1=O)NCC1CCC(C(=O)NCCN2C(=O)C=CC2=O)CC1
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| InChI |
InChI=1S/C23H30N4O6/c28-18(3-1-2-13-26-19(29)8-9-20(26)30)25-15-16-4-6-17(7-5-16)23(33)24-12-14-27-21(31)10-11-22(27)32/h8-11,16-17H,1-7,12-15H2,(H,24,33)(H,25,28)
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| InChIKey |
VYRCXOSNXYVERQ-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
458.515
|
Polar area
|
132.96
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Complexity
|
33
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xlogp Value
|
0.0455
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Heavy Count
|
33
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Rot Bonds
|
11
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Hbond acc
|
6
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker
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