Linker Information
General Information of This Linker
| Linker ID |
LIN0HFWKI
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| Linker Name |
CN113549127A-ADC-17-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C42H70N8O16S
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| Isosmiles |
CC(C)[C@@H](NC(OCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC#CC1=CN=C(S)N=C1)=O)=O)=O)C(N[C@H](C(O)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C42H70N8O16S/c1-32(2)37(38(53)49-34(39(54)55)8-6-10-46-40(43)56)50-42(57)66-31-36(52)45-12-14-59-16-18-61-20-22-63-24-26-65-28-27-64-25-23-62-21-19-60-17-15-58-13-11-44-35(51)9-5-3-4-7-33-29-47-41(67)48-30-33/h29-30,32,34,37H,3,5-6,8-28,31H2,1-2H3,(H,44,51)(H,45,52)(H,49,53)(H,50,57)(H,54,55)(H3,43,46,56)(H,47,48,67)/t34-,37+/m0/s1
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| InChIKey |
IKVGSZFQACZEAP-PIZIKKFZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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975.129
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Polar area
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317.67
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Complexity
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1496.684813
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xlogp Value
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-0.579
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Heavy Count
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67
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Rot Bonds
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41
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Hbond acc
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18
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Hbond Donor
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8
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Each Antibody-drug Conjugate Related to This Linker