Linker Information
General Information of This Linker
| Linker ID |
LIN0HEZZO
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| Linker Name |
CN113549127A-ADC-25-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H37N5O7S2
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| Isosmiles |
CC(C)[C@H](NC(CCCCCN1C(C(CS)=C(CS)C1=O)=O)=O)C(N[C@H](C(O)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C23H37N5O7S2/c1-13(2)18(19(30)26-16(22(33)34)7-6-9-25-23(24)35)27-17(29)8-4-3-5-10-28-20(31)14(11-36)15(12-37)21(28)32/h13,16,18,36-37H,3-12H2,1-2H3,(H,26,30)(H,27,29)(H,33,34)(H3,24,25,35)/t16-,18-/m0/s1
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| InChIKey |
LIVGDPSSYBZVFX-WMZOPIPTSA-N
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| Pharmaceutical Properties |
Molecule Weight
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559.711
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Polar area
|
188
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Complexity
|
828.4692002
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xlogp Value
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0.2305
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Heavy Count
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37
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Rot Bonds
|
17
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Hbond acc
|
8
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker