Linker Information
General Information of This Linker
| Linker ID |
LIN0HEYJF
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| Linker Name |
WO2023173026A1-ADC-L081-034-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H48N6O8
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| Isosmiles |
CN(C)CCN(CCNC(CCOCCOCCOCCOCCC(O)=O)=O)CCNC(C1=CC=C(N)C(N)=C1)=O
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| InChI |
InChI=1S/C27H48N6O8/c1-32(2)11-12-33(10-8-31-27(37)22-3-4-23(28)24(29)21-22)9-7-30-25(34)5-13-38-15-17-40-19-20-41-18-16-39-14-6-26(35)36/h3-4,21H,5-20,28-29H2,1-2H3,(H,30,34)(H,31,37)(H,35,36)
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| InChIKey |
SFCLMIDVTRVNKI-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
584.715
|
Polar area
|
190.94
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Complexity
|
837.5943257
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xlogp Value
|
-0.5082
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Heavy Count
|
41
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Rot Bonds
|
25
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker