Linker Information
General Information of This Linker
| Linker ID |
LIN0HEJUX
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| Linker Name |
IG-L-58 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C62H85N15O21
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| Isosmiles |
CN(CC(N(C)CC(N(CC(N(CC(N(C)CC(N(C)CC(N(CC(N(C)CC(N(CC(O)=O)C)=O)=O)C)=O)=O)=O)C)=O)C)=O)=O)C(CN(C)C(CCCOC1=CC(N2C(C=CC2=O)=O)=CC=C1CCC(NCC(NCC(N[C@@H](CC3=CC=CC=C3)C(NCC(O)=O)=O)=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C62H85N15O21/c1-67(30-51(84)68(2)31-52(85)69(3)32-53(86)70(4)33-54(87)71(5)34-55(88)72(6)35-56(89)73(7)36-57(90)74(8)37-58(91)75(9)38-59(92)76(10)39-61(95)96)48(81)17-14-24-98-44-26-42(77-49(82)22-23-50(77)83)20-18-41(44)19-21-45(78)63-27-46(79)64-28-47(80)66-43(62(97)65-29-60(93)94)25-40-15-12-11-13-16-40/h11-13,15-16,18,20,22-23,26,43H,14,17,19,21,24-25,27-39H2,1-10H3,(H,63,78)(H,64,79)(H,65,97)(H,66,80)(H,93,94)(H,95,96)/t43-/m0/s1
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| InChIKey |
GKHLWBFQLWTGPB-QLKFWGTOSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1376.446
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Polar area
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440.71
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Complexity
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3218.820796
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xlogp Value
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-5.9631
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Heavy Count
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98
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Rot Bonds
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39
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Hbond acc
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19
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker