Linker Information
General Information of This Linker
| Linker ID |
LIN0HEIOI
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|---|---|---|---|---|---|---|
| Linker Name |
Mal-glucuronidase cleavable linker
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| Linker Type |
Glycosidases-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H28N2O11
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| Isosmiles |
O=C(CN1C(=O)C=CC1=O)NCCCCc1ccc(CO)c(OC2OC(C(=O)O)C(O)C(O)C2O)c1
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| InChI |
InChI=1S/C23H28N2O11/c26-11-13-5-4-12(3-1-2-8-24-15(27)10-25-16(28)6-7-17(25)29)9-14(13)35-23-20(32)18(30)19(31)21(36-23)22(33)34/h4-7,9,18-21,23,26,30-32H,1-3,8,10-11H2,(H,24,27)(H,33,34)
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| InChIKey |
UQFWCNYEGQFGME-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
508.48
|
Polar area
|
203.16
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Complexity
|
36
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xlogp Value
|
-2.1862
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Heavy Count
|
36
|
Rot Bonds
|
11
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Hbond acc
|
10
|
Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker
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