Linker Information
General Information of This Linker
| Linker ID |
LIN0HBYHK
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| Linker Name |
TW202506738A-C-102-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C38H64N6O17
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCNC(CC[C@@H](NC(CCCN1C(C=CC1=O)=O)=O)C(NCCCC(NCC(NCC(O)=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C38H64N6O17/c1-54-14-15-56-18-19-58-22-23-60-26-27-61-25-24-59-21-20-57-17-16-55-13-11-39-32(46)7-6-30(43-33(47)5-3-12-44-35(49)8-9-36(44)50)38(53)40-10-2-4-31(45)41-28-34(48)42-29-37(51)52/h8-9,30H,2-7,10-29H2,1H3,(H,39,46)(H,40,53)(H,41,45)(H,42,48)(H,43,47)(H,51,52)/t30-/m1/s1
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| InChIKey |
CMDQHINBPHLHST-SSEXGKCCSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
876.955
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Polar area
|
294.02
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Complexity
|
1242.483129
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xlogp Value
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-2.9512
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Heavy Count
|
61
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Rot Bonds
|
41
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Hbond acc
|
16
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker