Linker Information
General Information of This Linker
| Linker ID |
LIN0GWLIO
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|---|---|---|---|---|---|---|
| Linker Name |
N-succinimidyl iodoacetate (SIA)
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C6H6INO4
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| Isosmiles |
C1CC(=O)N(C1=O)OC(=O)CI
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| PubChem CID | ||||||
| InChI |
InChI=1S/C6H6INO4/c7-3-6(11)12-8-4(9)1-2-5(8)10/h1-3H2
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| InChIKey |
VRDGQQTWSGDXCU-UHFFFAOYSA-N
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| IUPAC Name |
(2,5-dioxopyrrolidin-1-yl) 2-iodoacetate
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| Pharmaceutical Properties |
Molecule Weight
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283.02
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Polar area
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63.7
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Complexity
|
224
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xlogp Value
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-0.1
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Heavy Count
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12
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Rot Bonds
|
3
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Hbond acc
|
4
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Hbond Donor
|
0
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Each Antibody-drug Conjugate Related to This Linker
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