Linker Information
General Information of This Linker
| Linker ID |
LIN0GWAUV
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| Linker Name |
TWI870307BAntibody-drug conjugate (36)Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H27N4O8
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| Isosmiles |
O=C(NCC(O)=O)[C@@H](NC(CNC(C[N]C(CCCC1C(C=CC1=O)=O)=O)=O)=O)CC2=CC=CC=C2
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| InChI |
InChI=1S/C24H27N4O8/c29-18-9-10-19(30)16(18)7-4-8-20(31)25-12-21(32)26-13-22(33)28-17(24(36)27-14-23(34)35)11-15-5-2-1-3-6-15/h1-3,5-6,9-10,16-17H,4,7-8,11-14H2,(H,26,32)(H,27,36)(H,28,33)(H,34,35)/t17-/m0/s1
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| InChIKey |
GDDSMDFSJRGKDP-KRWDZBQOSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
499.5
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Polar area
|
189.91
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Complexity
|
975.7337252
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xlogp Value
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-1.3436
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Heavy Count
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36
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Rot Bonds
|
14
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Hbond acc
|
7
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker