Linker Information
General Information of This Linker
| Linker ID |
LIN0GVPVD
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|---|---|---|---|---|---|---|
| Linker Name |
DBCO-C6-PEG8-VC-PABC-AE
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C58H82N6O15
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| Isosmiles |
CC(C)[C@H](NC(CCOCCOCCOCCOCCOCCOCCOCCOCCNC(CCCC(N1CC2=C(C#CC3=C1C=CC=C3)C=CC=C2)=O)=O)=O)C(N[C@H](C(NC4=CC=C(CO)C=C4)=O)CCCCC(N)=O)=O
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| InChI |
InChI=1S/C58H82N6O15/c1-44(2)56(58(71)62-50(13-6-8-15-52(59)66)57(70)61-49-22-18-45(43-65)19-23-49)63-54(68)24-26-72-28-30-74-32-34-76-36-38-78-40-41-79-39-37-77-35-33-75-31-29-73-27-25-60-53(67)16-9-17-55(69)64-42-48-12-4-3-10-46(48)20-21-47-11-5-7-14-51(47)64/h3-5,7,10-12,14,18-19,22-23,44,50,56,65H,6,8-9,13,15-17,24-43H2,1-2H3,(H2,59,66)(H,60,67)(H,61,70)(H,62,71)(H,63,68)/t50-,56-/m0/s1
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| InChIKey |
XMLAHLRIRZSSSP-SKXIGKDTSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
1103.321
|
Polar area
|
273.87
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Complexity
|
2259.068154
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xlogp Value
|
3.5447
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Heavy Count
|
79
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Rot Bonds
|
43
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Hbond acc
|
15
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker