Linker Information
General Information of This Linker
| Linker ID |
LIN0GTVPC
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| Linker Name |
Linker of ADC3-16
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C31H49N5O12
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| Isosmiles |
CC([C@H](NC([C@@H](NC(CCCCCN1C(C=CC1=O)=O)=O)CCC(NC[C@H](O2)[C@H](O)[C@@H](O)[C@@H](O)[C@H]2CO)=C)=O)C(N[C@@H](C)C(O)=O)=O)C
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| InChI |
InChI=1S/C31H49N5O12/c1-16(2)25(30(45)33-18(4)31(46)47)35-29(44)19(34-22(38)8-6-5-7-13-36-23(39)11-12-24(36)40)10-9-17(3)32-14-20-26(41)28(43)27(42)21(15-37)48-20/h11-12,16,18-21,25-28,32,37,41-43H,3,5-10,13-15H2,1-2,4H3,(H,33,45)(H,34,38)(H,35,44)(H,46,47)/t18-,19-,20-,21+,25-,26-,27-,28+/m0/s1
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| InChIKey |
NQGAFZAALSRNME-OOZXOQOASA-N
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| Pharmaceutical Properties |
Molecule Weight
|
683.756
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Polar area
|
264.16
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Complexity
|
1130.418625
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xlogp Value
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-2.5874
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Heavy Count
|
48
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Rot Bonds
|
20
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Hbond acc
|
12
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker