Linker Information
General Information of This Linker
| Linker ID |
LIN0GSWHZ
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| Linker Name |
Mc-PEG4-Val-Cit-PABC-DMAE
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C43H69N9O13
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| Isosmiles |
CC(C)C(NC(=O)CCOCCOCCOCCOCCNC(=O)CCCCCN1C(=O)C=CC1=O)C(=O)NC(CCCNC(N)=O)C(=O)Nc1ccc(COC(=O)N(C)CCN)cc1
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| InChI |
InChI=1S/C43H69N9O13/c1-31(2)39(41(58)49-34(8-7-18-47-42(45)59)40(57)48-33-12-10-32(11-13-33)30-65-43(60)51(3)21-17-44)50-36(54)16-22-61-24-26-63-28-29-64-27-25-62-23-19-46-35(53)9-5-4-6-20-52-37(55)14-15-38(52)56/h10-15,31,34,39H,4-9,16-30,44H2,1-3H3,(H,46,53)(H,48,57)(H,49,58)(H,50,54)(H3,45,47,59)
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| InChIKey |
SIRXAFLFOXOXTL-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
920.075
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Polar area
|
301.38
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Complexity
|
65
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xlogp Value
|
0.2844
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Heavy Count
|
65
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Rot Bonds
|
35
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Hbond acc
|
14
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker
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