Linker Information
General Information of This Linker
| Linker ID |
LIN0GSOCY
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|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-400-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C41H71N5O18
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@H](NC(CCCN1C(C=CC1=O)=O)=O)C(NCC(NCCCC(O)=O)=O)=O)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C41H71N5O18/c1-55-14-15-56-16-17-57-18-19-58-20-21-59-22-23-60-24-25-61-26-27-62-28-29-63-30-31-64-33-37(49)43-11-3-2-6-34(41(54)44-32-36(48)42-12-4-8-40(52)53)45-35(47)7-5-13-46-38(50)9-10-39(46)51/h9-10,34H,2-8,11-33H2,1H3,(H,42,48)(H,43,49)(H,44,54)(H,45,47)(H,52,53)/t34-/m0/s1
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| InChIKey |
NCFLARVVVDEHAK-UMSFTDKQSA-N
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| Pharmaceutical Properties |
Molecule Weight
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922.036
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Polar area
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283.38
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Complexity
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1230.383091
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xlogp Value
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-1.6441
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Heavy Count
|
64
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Rot Bonds
|
46
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Hbond acc
|
17
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker