Linker Information
General Information of This Linker
| Linker ID |
LIN0GOVIC
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| Linker Name |
TW202506738A-C-397-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C44H68N6O20
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| Isosmiles |
OCCOCCOCCOCCOCCOCCOCCOCCOCC(NCCCC[C@@H](C(NCCCC(O)=O)O)NC(CCCN1C([C@H]([C@@H](C1=O)N2C(C=CC2=O)=O)N3C(C=CC3=O)=O)=O)=O)=O
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| InChI |
InChI=1S/C44H68N6O20/c51-15-16-63-17-18-64-19-20-65-21-22-66-23-24-67-25-26-68-27-28-69-29-30-70-31-34(53)45-12-2-1-5-32(42(60)46-13-3-7-39(58)59)47-33(52)6-4-14-48-43(61)40(49-35(54)8-9-36(49)55)41(44(48)62)50-37(56)10-11-38(50)57/h8-11,32,40-42,46,51,60H,1-7,12-31H2,(H,45,53)(H,47,52)(H,58,59)/t32-,40-,41-,42?/m0/s1
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| InChIKey |
QHRSXPMSXKQLKF-FVSRZNKESA-N
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| Pharmaceutical Properties |
Molecule Weight
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1001.05
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Polar area
|
333.97
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Complexity
|
1567.858568
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xlogp Value
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-3.6082
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Heavy Count
|
70
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Rot Bonds
|
43
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Hbond acc
|
20
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker