Linker Information
General Information of This Linker
| Linker ID |
LIN0GOLMA
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| Linker Name |
Gly3-VC-PAB
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H38N8O9
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| Isosmiles |
CC(C(NC(CNC(CNC(CN)=O)=O)=O)C(N[C@@H](CCCNC(N)=O)C(NC1=CC=C(COC(O)=O)C=C1)=O)=O)C
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| InChI |
InChI=1S/C25H38N8O9/c1-14(2)21(33-20(36)12-30-19(35)11-29-18(34)10-26)23(38)32-17(4-3-9-28-24(27)39)22(37)31-16-7-5-15(6-8-16)13-42-25(40)41/h5-8,14,17,21H,3-4,9-13,26H2,1-2H3,(H,29,34)(H,30,35)(H,31,37)(H,32,38)(H,33,36)(H,40,41)(H3,27,28,39)/t17-,21?/m0/s1
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| InChIKey |
MWRFYUFOASMUBG-PBVYKCSPSA-N
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| Pharmaceutical Properties |
Molecule Weight
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594.626
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Polar area
|
273.17
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Complexity
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1053.760458
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xlogp Value
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-1.9151
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Heavy Count
|
42
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker