Linker Information
General Information of This Linker
| Linker ID |
LIN0GNRPN
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| Linker Name |
IL316790A-2linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C45H66N10O11
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| Isosmiles |
CN1CC(N2CCC(N[C@@H](C(NCCOCCOCCC(NC(C(C)C)C(N[C@@H](C(NC3=CC=C(CO)C=C3)=O)CCCNC(N)=O)=O)=O)=O)CCC(O)=O)=O)=C(C4=C2C=CC=C4)CN1C
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| InChI |
InChI=1S/C45H66N10O11/c1-29(2)41(44(63)51-34(9-7-19-48-45(46)64)43(62)49-31-13-11-30(28-56)12-14-31)52-39(58)18-22-65-24-25-66-23-20-47-42(61)35(15-16-40(59)60)50-38(57)17-21-55-36-10-6-5-8-32(36)33-26-53(3)54(4)27-37(33)55/h5-6,8,10-14,29,34-35,41,56H,7,9,15-28H2,1-4H3,(H,47,61)(H,49,62)(H,50,57)(H,51,63)(H,52,58)(H,59,60)(H3,46,48,64)/t34-,35-,41?/m1/s1
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| InChIKey |
YKTIUAIMNFGHJX-ZIUGMFATSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
923.082
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Polar area
|
288.02
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Complexity
|
2032.124225
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xlogp Value
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0.9178
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Heavy Count
|
66
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Rot Bonds
|
28
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Hbond acc
|
13
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker