Linker Information
General Information of This Linker
| Linker ID |
LIN0GNIRY
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|---|---|---|---|---|---|---|
| Linker Name |
Linker105
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C22H30N6O6
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| Isosmiles |
[H][C@@]12CCC(N=NN3)=C3CC[C@]1([H])[C@@H]2COC(O)=O.[H][C@]45CCC6=C(N=NN6)CC[C@@]4([H])[C@H]5COC(O)=O
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| InChI |
InChI=1S/2C11H15N3O3/c2*15-11(16)17-5-8-6-1-3-9-10(13-14-12-9)4-2-7(6)8/h2*6-8H,1-5H2,(H,15,16)(H,12,13,14)/t2*6-,7+,8-
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| InChIKey |
MMGHMPUIAQOAAL-VSCSFYFDSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
474.518
|
Polar area
|
176.2
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Complexity
|
842.1054608
|
xlogp Value
|
2.4806
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Heavy Count
|
34
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Rot Bonds
|
4
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Hbond acc
|
8
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker