Linker Information
General Information of This Linker
| Linker ID |
LIN0GCBSE
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| Linker Name |
WO2024099368A1+Tra-CAST-MMAE+Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C33H44N6O5
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| Isosmiles |
CC(C(NC(C(CC1)CCN1CC2=CC=C(C=C2)C#C)=O)C(N[C@@H](CCCNC(N)=O)C(NC3=CC=C(CO)C=C3)=O)=O)C
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| InChI |
InChI=1S/C33H44N6O5/c1-4-23-7-9-24(10-8-23)20-39-18-15-26(16-19-39)30(41)38-29(22(2)3)32(43)37-28(6-5-17-35-33(34)44)31(42)36-27-13-11-25(21-40)12-14-27/h1,7-14,22,26,28-29,40H,5-6,15-21H2,2-3H3,(H,36,42)(H,37,43)(H,38,41)(H3,34,35,44)/t28-,29?/m0/s1
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| InChIKey |
GEWOKJTWBHQQES-XLTVJXRZSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
604.752
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Polar area
|
165.89
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Complexity
|
1250.81356
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xlogp Value
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2.085
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Heavy Count
|
44
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Rot Bonds
|
14
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Hbond acc
|
6
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker