General Information of This Linker
Linker ID
LIN0FYWXF
Linker Name
Disulfide linker
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C16H19N3O5S2
Isosmiles
C[C@@H](SSC1=CC=C(N(O)O)N=C1)COC(NC2=CC=C(CO)C=C2)=O
InChI
InChI=1S/C16H19N3O5S2/c1-11(25-26-14-6-7-15(17-8-14)19(22)23)10-24-16(21)18-13-4-2-12(9-20)3-5-13/h2-8,11,20,22-23H,9-10H2,1H3,(H,18,21)/t11-/m1/s1
InChIKey
XWDIABZSGZIROA-LLVKDONJSA-N
Pharmaceutical Properties
Molecule Weight
397.478
Polar area
115.15
Complexity
658.1894279
xlogp Value
3.5362
Heavy Count
26
Rot Bonds
8
Hbond acc
9
Hbond Donor
4
Each Antibody-drug Conjugate Related to This Linker