Linker Information
General Information of This Linker
| Linker ID |
LIN0FYFAD
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| Linker Name |
L103 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C87H154N10O38
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| Isosmiles |
CN(C(OCC1=CC=C(NC([C@@H](NC([C@@H](NC(CCOCCN2C(C=CC2=O)=O)=O)C(C)C)=O)CCCNC(N)=O)=O)C=C1CN(C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O)=O)C)=O)CCN(C)C(O)=O
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| InChI |
InChI=1S/C87H154N10O38/c1-72(2)81(93-77(98)12-19-110-22-18-97-78(99)10-11-79(97)100)83(104)92-76(7-6-14-89-84(88)105)82(103)91-75-9-8-73(71-135-87(109)95(4)17-16-94(3)86(107)108)74(69-75)70-96(5)85(106)90-15-21-112-24-26-114-28-30-116-32-34-118-36-38-120-40-42-122-44-46-124-48-50-126-52-54-128-56-58-130-60-62-132-64-66-134-68-67-133-65-63-131-61-59-129-57-55-127-53-51-125-49-47-123-45-43-121-41-39-119-37-35-117-33-31-115-29-27-113-25-23-111-20-13-80(101)102/h8-11,69,72,76,81H,6-7,12-68,70-71H2,1-5H3,(H,90,106)(H,91,103)(H,92,104)(H,93,98)(H,101,102)(H,107,108)(H3,88,89,105)/t76-,81-/m0/s1
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| InChIKey |
KAHUPIGNOKUOLT-YKZHOSDFSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1948.221
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Polar area
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550.27
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Complexity
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.
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xlogp Value
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0.2236
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Heavy Count
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135
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Rot Bonds
|
98
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Hbond acc
|
36
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Hbond Donor
|
8
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Each Antibody-drug Conjugate Related to This Linker