Linker Information
General Information of This Linker
| Linker ID |
LIN0FVYMD
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| Linker Name |
IG-L-70 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C84H128FN23O29
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| Isosmiles |
CC[C@H](NC([C@H](C)NC(CCC1=CC=C(N2C(C=CC2=O)=O)C(F)=C1OCCCC(N(CC(N(CC(N(C)CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(C)CC(N(CC(N(C)CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(N(CC(N(C)CC(O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)C)=O)=O)=O)C)=O)=O)C)=O)=O)C)=O)=O)=O)C)=O)C)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C84H128FN23O29/c1-23-55(84(135)136)87-83(134)53(2)86-57(109)29-27-54-26-28-56(108-59(111)30-31-60(108)112)81(85)82(54)137-32-24-25-58(110)88(3)33-61(113)89(4)34-62(114)90(5)35-63(115)91(6)36-64(116)92(7)37-65(117)93(8)38-66(118)94(9)39-67(119)95(10)40-68(120)96(11)41-69(121)97(12)42-70(122)98(13)43-71(123)99(14)44-72(124)100(15)45-73(125)101(16)46-74(126)102(17)47-75(127)103(18)48-76(128)104(19)49-77(129)105(20)50-78(130)106(21)51-79(131)107(22)52-80(132)133/h26,28,30-31,53,55H,23-25,27,29,32-52H2,1-22H3,(H,86,109)(H,87,134)(H,132,133)(H,135,136)/t53-,55-/m0/s1
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| InChIKey |
FLDRMDCYCMDVGQ-KLJYSMPWSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1943.078
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Polar area
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585.61
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Complexity
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.
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xlogp Value
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-9.9166
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Heavy Count
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137
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Rot Bonds
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54
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Hbond acc
|
27
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker