Linker Information
General Information of This Linker
| Linker ID |
LIN0FQQTV
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| Linker Name |
CHH0187, 10i-5657, Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C33H51N5O13
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| Isosmiles |
CC(C)[C@H](NC(C1CCCN1C([C@@H](NC(CCOCCOCCOCCNC(CCCCCN2C(C=CC2=O)=O)=O)=O)CC(O)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C33H51N5O13/c1-22(2)30(33(47)48)36-31(45)24-7-6-14-37(24)32(46)23(21-29(43)44)35-26(40)11-15-49-17-19-51-20-18-50-16-12-34-25(39)8-4-3-5-13-38-27(41)9-10-28(38)42/h9-10,22-24,30H,3-8,11-21H2,1-2H3,(H,34,39)(H,35,40)(H,36,45)(H,43,44)(H,47,48)/t23-,24?,30-/m0/s1
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| InChIKey |
LSGCMSZEAIFBNT-FNEOLHDUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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725.793
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Polar area
|
247.28
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Complexity
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1176.262704
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xlogp Value
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-0.7962
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Heavy Count
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51
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Rot Bonds
|
26
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Hbond acc
|
11
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker