Linker Information
General Information of This Linker
| Linker ID |
LIN0FQNAY
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| Linker Name |
CN114450324B-ADC-39-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C87H145N7O38
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| Isosmiles |
O=C(CCNC(OCC(COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)(NC(CCNC(CCN1C(C=CC1=O)=O)=O)=O)COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)NC(C(NCC(NC2=CC=C(COC(O)=O)C=C2)=O)=O)CC3=CC=CC=C3
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| InChI |
InChI=1S/C87H145N7O38/c1-105-20-22-107-24-26-109-28-30-111-32-34-113-36-38-115-40-42-117-44-46-119-48-50-121-52-54-123-56-58-125-60-62-127-64-66-129-71-87(93-80(97)15-17-88-78(95)16-19-94-82(99)12-13-83(94)100,73-132-85(102)89-18-14-79(96)92-77(68-74-6-4-3-5-7-74)84(101)90-69-81(98)91-76-10-8-75(9-11-76)70-131-86(103)104)72-130-67-65-128-63-61-126-59-57-124-55-53-122-51-49-120-47-45-118-43-41-116-39-37-114-35-33-112-31-29-110-27-25-108-23-21-106-2/h3-13,77H,14-73H2,1-2H3,(H,88,95)(H,89,102)(H,90,101)(H,91,98)(H,92,96)(H,93,97)(H,103,104)
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| InChIKey |
RVIFBOYUUKFSGB-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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1897.128
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Polar area
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507.72
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Complexity
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.
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xlogp Value
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0.1473
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Heavy Count
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132
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Rot Bonds
|
97
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Hbond acc
|
37
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker