Linker Information
General Information of This Linker
| Linker ID |
LIN0FPGKY
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|---|---|---|---|---|---|---|
| Linker Name |
WO2024105205A1-8e-946-Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C9H15N3O5
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| Isosmiles |
O=C(N)CCCC(N[C@@H](CC(N)=O)C(O)=O)=O
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| InChI |
InChI=1S/C9H15N3O5/c10-6(13)2-1-3-8(15)12-5(9(16)17)4-7(11)14/h5H,1-4H2,(H2,10,13)(H2,11,14)(H,12,15)(H,16,17)/t5-/m0/s1
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| InChIKey |
AVKRZDLUKDCGRZ-YFKPBYRVSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
245.235
|
Polar area
|
152.58
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Complexity
|
304
|
xlogp Value
|
-1.9132
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Heavy Count
|
17
|
Rot Bonds
|
8
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Hbond acc
|
4
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker