General Information of This Linker
Linker ID
LIN0FLQUT
Linker Name
TWI857167B-IC-96-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C15H18F4O8S
Isosmiles
CCOCCOCCOCCC(OC1=C(F)C(F)=C(S(=O)(O)=O)C(F)=C1F)=O
InChI
InChI=1S/C15H18F4O8S/c1-2-24-5-6-26-8-7-25-4-3-9(20)27-14-10(16)12(18)15(28(21,22)23)13(19)11(14)17/h2-8H2,1H3,(H,21,22,23)
InChIKey
UKIZNYPFHIXCER-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
434.36
Polar area
108.36
Complexity
711.7283689
xlogp Value
1.8549
Heavy Count
28
Rot Bonds
12
Hbond acc
7
Hbond Donor
1
Each Antibody-drug Conjugate Related to This Linker