Linker Information
General Information of This Linker
| Linker ID |
LIN0FHCDX
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|---|---|---|---|---|---|---|
| Linker Name |
Ala-Val linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C10H17BrN2O4
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| Isosmiles |
OC([C@H](C(C)C)NC([C@H](C)NC(CBr)=O)=O)=O
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| InChI |
InChI=1S/C10H17BrN2O4/c1-5(2)8(10(16)17)13-9(15)6(3)12-7(14)4-11/h5-6,8H,4H2,1-3H3,(H,12,14)(H,13,15)(H,16,17)/t6-,8-/m0/s1
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| InChIKey |
YTZRUONBDBZLQV-XPUUQOCRSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
309.16
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Polar area
|
95.5
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Complexity
|
280.4134357
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xlogp Value
|
0.1114
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Heavy Count
|
17
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Rot Bonds
|
6
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Hbond acc
|
3
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker