Linker Information
General Information of This Linker
| Linker ID |
LIN0FGGIM
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| Linker Name |
Antibody-drug conjugate (5)Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H33N5O10
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| Isosmiles |
O=C(N1CCCCCC(N[C@H](C(NCC(NCC(N[C@@H](CC2=CC=CC=C2)C(O)=O)=O)=O)=O)CC(O)=O)=O)C=CC1=O
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| InChI |
InChI=1S/C27H33N5O10/c33-20(9-5-2-6-12-32-23(36)10-11-24(32)37)30-18(14-25(38)39)26(40)29-15-21(34)28-16-22(35)31-19(27(41)42)13-17-7-3-1-4-8-17/h1,3-4,7-8,10-11,18-19H,2,5-6,9,12-16H2,(H,28,34)(H,29,40)(H,30,33)(H,31,35)(H,38,39)(H,41,42)/t18-,19-/m0/s1
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| InChIKey |
MKBXKAWTUFPONG-OALUTQOASA-N
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| Pharmaceutical Properties |
Molecule Weight
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587.586
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Polar area
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228.38
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Complexity
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1145.649982
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xlogp Value
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-1.5242
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Heavy Count
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42
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Rot Bonds
|
18
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Hbond acc
|
8
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker