Linker Information
General Information of This Linker
| Linker ID |
LIN0FFPOL
|
|||||
|---|---|---|---|---|---|---|
| Linker Name |
CN119630431A-ADC-80-LINKER
|
|||||
| Linker Type |
Cathepsin-cleavable linker
|
|||||
| Antibody-Linker Relation |
Cleavable
|
|||||
| Structure |
|
|||||
| Formula |
C68H100N6O23S2
|
|||||
| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(NCCCC[C@H](NC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)C(NCC(N[C@@H](CC4=CC=CC=C4)C(NCC(O)=O)=O)=O)=O)=O
|
|||||
| InChI |
InChI=1S/C68H100N6O23S2/c1-84-27-28-88-33-34-90-37-38-92-41-42-94-45-46-96-49-50-97-48-47-95-44-43-93-40-39-91-36-35-89-32-30-85-24-20-59(75)69-22-12-11-19-57(65(80)70-52-61(77)73-58(66(81)71-53-62(78)79)51-54-13-5-2-6-14-54)72-60(76)21-25-86-29-31-87-26-23-74-67(82)63(98-55-15-7-3-8-16-55)64(68(74)83)99-56-17-9-4-10-18-56/h2-10,13-18,57-58H,11-12,19-53H2,1H3,(H,69,75)(H,70,80)(H,71,81)(H,72,76)(H,73,77)(H,78,79)/t57-,58-/m0/s1
|
|||||
| InChIKey |
UXGBOCHGDYWFFH-YQOHNZFASA-N
|
|||||
| Pharmaceutical Properties |
Molecule Weight
|
1433.701
|
Polar area
|
349.4
|
||
|
Complexity
|
2547.967867
|
xlogp Value
|
2.6096
|
|||
|
Heavy Count
|
99
|
Rot Bonds
|
64
|
|||
|
Hbond acc
|
24
|
Hbond Donor
|
6
|
|||
Each Antibody-drug Conjugate Related to This Linker