Linker Information
General Information of This Linker
| Linker ID |
LIN0FFKYA
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| Linker Name |
CN110997010A ADC-20 linker
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| Linker Type |
Uncleavable linker
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| Antibody-Linker Relation |
Uncleavable
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| Structure |
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| Formula |
C117H179N19O40S2
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| Isosmiles |
O=C(O)C(NC(C(NC(OCCOCCN1C(CCC1=O)=O)=O)CSC(CC2=O)C(N2CC3CCC(C(NCC(N=N4)=CC4CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](CCCCN)C(NC5=CC=C(C=C5)CO)=O)=O)=O)=O)=CC3)=O)=O)CSC(C6=O)CC(N6CC7CCC(C(NCC(N=N8)=CC8CCOCCOCCOCCOCCOCCOCCOCCOCCNC(COCC(N[C@H](CCCCN)C(NC9=CC=C(C=C9)CO)=O)=O)=O)=O)=CC7)=O
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| InChI |
InChI=1S/C117H179N19O40S2/c118-27-3-1-5-95(111(149)124-89-19-11-85(75-137)12-20-89)126-103(141)79-174-77-101(139)120-29-34-159-39-43-164-47-51-168-55-59-172-63-61-170-57-53-166-49-45-162-41-37-157-32-25-91-67-93(132-130-91)71-122-109(147)87-15-7-83(8-16-87)73-135-107(145)69-99(114(135)152)177-81-97(129-117(156)176-66-65-161-36-31-134-105(143)23-24-106(134)144)113(151)128-98(116(154)155)82-178-100-70-108(146)136(115(100)153)74-84-9-17-88(18-10-84)110(148)123-72-94-68-92(131-133-94)26-33-158-38-42-163-46-50-167-54-58-171-62-64-173-60-56-169-52-48-165-44-40-160-35-30-121-102(140)78-175-80-104(142)127-96(6-2-4-28-119)112(150)125-90-21-13-86(76-138)14-22-90/h11-15,17,19-22,67-68,83-84,91-92,95-100,137-138H,1-10,16,18,23-66,69-82,118-119H2,(H,120,139)(H,121,140)(H,122,147)(H,123,148)(H,124,149)(H,125,150)(H,126,141)(H,127,142)(H,128,151)(H,129,156)(H,154,155)/t83?,84?,91?,92?,95-,96-,97?,98?,99?,100?/m1/s1
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| InChIKey |
BSKPDSOXJRAHGI-BVSHBYIKSA-N
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| Pharmaceutical Properties |
Molecule Weight
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2555.946
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Polar area
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766.98
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Complexity
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.
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xlogp Value
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0.4606
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Heavy Count
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178
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Rot Bonds
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104
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Hbond acc
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47
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Hbond Donor
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15
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Each Antibody-drug Conjugate Related to This Linker