Linker Information
General Information of This Linker
| Linker ID |
LIN0FEVAD
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| Linker Name |
CN117362435A+SCD44-MMAE+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H38N6O9
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| Isosmiles |
CC(C)[C@@H](NC(CCCCC(ON1C(C=CC1=O)=O)=O)=O)C(N[C@H](C(NC2=CC=C(CO)C=C2)=O)CCCNC(N)=O)=O
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| InChI |
InChI=1S/C28H38N6O9/c1-17(2)25(33-21(36)7-3-4-8-24(39)43-34-22(37)13-14-23(34)38)27(41)32-20(6-5-15-30-28(29)42)26(40)31-19-11-9-18(16-35)10-12-19/h9-14,17,20,25,35H,3-8,15-16H2,1-2H3,(H,31,40)(H,32,41)(H,33,36)(H3,29,30,42)/t20-,25+/m0/s1
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| InChIKey |
CRGDMIPXEXGHSR-NBGIEHNGSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
602.645
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Polar area
|
226.33
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Complexity
|
1142.895094
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xlogp Value
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0.1351
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Heavy Count
|
43
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Rot Bonds
|
17
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Hbond acc
|
9
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker