Linker Information
General Information of This Linker
| Linker ID |
LIN0FCZCY
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| Linker Name |
C-Lock-ANN tri-peptide
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| Linker Type |
Site-specific conjugation linker; Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H37Br2N7O9
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| Isosmiles |
CC(NC(=O)CCOCCOCCNC(=O)c1ccc2nc(CBr)c(CBr)nc2c1)C(=O)NC(C)C(=O)NC(CC(N)=O)C(=O)O
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| InChI |
InChI=1S/C28H37Br2N7O9/c1-15(25(40)34-16(2)26(41)37-20(28(43)44)12-23(31)38)33-24(39)5-7-45-9-10-46-8-6-32-27(42)17-3-4-18-19(11-17)36-22(14-30)21(13-29)35-18/h3-4,11,15-16,20H,5-10,12-14H2,1-2H3,(H2,31,38)(H,32,42)(H,33,39)(H,34,40)(H,37,41)(H,43,44)
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| InChIKey |
GDEHUJMZJRMUDX-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
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775.452
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Polar area
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241.03
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Complexity
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46
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xlogp Value
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0.0269
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Heavy Count
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46
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Rot Bonds
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20
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Hbond acc
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10
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Hbond Donor
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6
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Each Antibody-drug Conjugate Related to This Linker
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