Linker Information
General Information of This Linker
| Linker ID |
LIN0FCMHV
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| Linker Name |
CN119072334A+ThioBridge⑩-Glu-[ (Val-Cit-PAB-MMáE)]2-Glu-[PEG (24u)]2+Linker
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| Linker Type |
Unclear
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| Antibody-Linker Relation |
Unclear
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| Structure |
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| Formula |
C196H313N17O74S2
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| Isosmiles |
CC([C@@H](NC(CC[C@H](NC([C@@H](NC(C1=CC=C(C(C(CS(C2=CC=C(C=C2)C)(=O)=O)CS(C3=CC=C(C=C3)C)(=O)=O)=O)C=C1)=O)CCC(N[C@@H](CC)C(N[C@H](C(NC4=CC=C(CO)C=C4)=O)CCCNC(N)=O)=O)=O)=O)C(N[C@@H](CCC(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)C(NCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOC)=O)=O)=O)C(N[C@H](C(NC5=CC=C(COC(O[C@](C(C=C6C7=C(C(CC)=C(C=C(O)C=C8)C8=N7)CN96)=C(C9=O)CO%10)(CC)C%10=O)=O)C=C5)=O)CCCNC(N)=O)=O)C
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| InChI |
InChI=1S/C196H313N17O74S2/c1-10-164-165-143-161(215)33-38-170(165)206-181-166(164)145-213-176(181)144-168-167(191(213)228)148-285-192(229)196(168,12-3)287-195(232)286-147-155-23-31-160(32-24-155)204-187(224)172(16-14-46-202-194(198)231)211-190(227)180(151(4)5)212-179(218)44-41-175(210-188(225)174(40-43-178(217)205-169(11-2)185(222)208-171(15-13-45-201-193(197)230)186(223)203-159-29-21-154(146-214)22-30-159)207-183(220)157-27-25-156(26-28-157)182(219)158(149-288(233,234)162-34-17-152(6)18-35-162)150-289(235,236)163-36-19-153(7)20-37-163)189(226)209-173(184(221)200-48-50-240-56-58-244-64-66-248-72-74-252-80-82-256-88-90-260-96-98-264-104-106-268-112-114-272-120-122-276-128-130-280-136-138-284-142-140-282-134-132-278-126-124-274-118-116-270-110-108-266-102-100-262-94-92-258-86-84-254-78-76-250-70-68-246-62-60-242-54-52-238-9)39-42-177(216)199-47-49-239-55-57-243-63-65-247-71-73-251-79-81-255-87-89-259-95-97-263-103-105-267-111-113-271-119-121-275-127-129-279-135-137-283-141-139-281-133-131-277-125-123-273-117-115-269-109-107-265-101-99-261-93-91-257-85-83-253-77-75-249-69-67-245-61-59-241-53-51-237-8/h17-38,143-144,151,158,169,171-175,180,214-215H,10-16,39-142,145-150H2,1-9H3,(H,199,216)(H,200,221)(H,203,223)(H,204,224)(H,205,217)(H,207,220)(H,208,222)(H,209,226)(H,210,225)(H,211,227)(H,212,218)(H3,197,201,230)(H3,198,202,231)/t169-,171-,172-,173-,174-,175-,180+,196-/m0/s1
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| InChIKey |
ROIAQRUWLADMFO-PNLXCDNUSA-N
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| Pharmaceutical Properties |
Molecule Weight
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4155.839
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Polar area
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1095.91
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Complexity
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.
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xlogp Value
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5.44154
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Heavy Count
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289
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Rot Bonds
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194
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Hbond acc
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76
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Hbond Donor
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17
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Each Antibody-drug Conjugate Related to This Linker