Linker Information
General Information of This Linker
| Linker ID |
LIN0FBIEI
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| Linker Name |
Anti-Her2-AL1- LP10 linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C37H55N7O17
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| Isosmiles |
NCCOCCOCCOCCN(N=N1)C2=C1CC(OCC(NCCNC(C3=C(O[C@H](O4)[C@H](O)[C@@H](O)[C@H](O)[C@H]4C(O)=O)C=CC(COC(NCC(O)=O)=O)=C3)=O)=O)CCCC2
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| InChI |
InChI=1S/C37H55N7O17/c38-7-11-55-13-15-57-16-14-56-12-10-44-26-4-2-1-3-23(18-25(26)42-43-44)58-21-28(45)39-8-9-40-34(51)24-17-22(20-59-37(54)41-19-29(46)47)5-6-27(24)60-36-32(50)30(48)31(49)33(61-36)35(52)53/h5-6,17,23,30-33,36,48-50H,1-4,7-16,18-21,38H2,(H,39,45)(H,40,51)(H,41,54)(H,46,47)(H,52,53)/t23?,30-,31-,32+,33-,36+/m0/s1
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| InChIKey |
BHLBGRBJBLLIEK-LKYLQNNWSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
869.879
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Polar area
|
343.93
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Complexity
|
1652.11451
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xlogp Value
|
-2.9313
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Heavy Count
|
61
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Rot Bonds
|
25
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Hbond acc
|
19
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Hbond Donor
|
9
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Each Antibody-drug Conjugate Related to This Linker