Linker Information
General Information of This Linker
| Linker ID |
LIN0FAQPJ
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| Linker Name |
WO2022197877A1+compound 4+Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H38N6O7
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| Isosmiles |
NC(NCCC[C@H](NC(C1(CCC1)C(NCCCCCN2C(C=CC2=O)=O)=O)=O)C(NC3=CC=C(CO)C=C3)=O)=O
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| PubChem CID | ||||||
| InChI |
InChI=1S/C28H38N6O7/c29-27(41)31-16-4-6-21(24(38)32-20-9-7-19(18-35)8-10-20)33-26(40)28(13-5-14-28)25(39)30-15-2-1-3-17-34-22(36)11-12-23(34)37/h7-12,21,35H,1-6,13-18H2,(H,30,39)(H,32,38)(H,33,40)(H3,29,31,41)/t21-/m0/s1
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| InChIKey |
HLAKJCQSHGCDPL-NRFANRHFSA-N
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| Pharmaceutical Properties |
Molecule Weight
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570.647
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Polar area
|
200.03
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Complexity
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1095.074443
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xlogp Value
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0.4325
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Heavy Count
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41
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Rot Bonds
|
16
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Hbond acc
|
7
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Hbond Donor
|
6
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Each Antibody-drug Conjugate Related to This Linker