General Information of This Linker
Linker ID
LIN0FAARM
Linker Name
TWI857167B-IC-30-LINKER
Linker Type
Cathepsin-cleavable linker
Antibody-Linker Relation
Cleavable
Structure
Formula
C31H48F4O13
Isosmiles
O=C(CC1=C(F)C(F)=CC(F)=C1F)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCC(O)=O
InChI
InChI=1S/C31H48F4O13/c32-27-24-28(33)31(35)26(30(27)34)23-25(36)1-3-39-5-7-41-9-11-43-13-15-45-17-19-47-21-22-48-20-18-46-16-14-44-12-10-42-8-6-40-4-2-29(37)38/h24H,1-23H2,(H,37,38)
InChIKey
MYFXQMZSEFWJKD-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
704.704
Polar area
146.67
Complexity
890.2062678
xlogp Value
2.3854
Heavy Count
48
Rot Bonds
35
Hbond acc
12
Hbond Donor
1
Each Antibody-drug Conjugate Related to This Linker