Linker Information
General Information of This Linker
| Linker ID |
LIN0EZVIA
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| Linker Name |
CN119630431A-ADC-67-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C27H29N3O8S2
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| Isosmiles |
O=C(N)C[C@H](NC(CCOCCOCCN1C(C(SC2=CC=CC=C2)=C(SC3=CC=CC=C3)C1=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C27H29N3O8S2/c28-21(31)17-20(27(35)36)29-22(32)11-13-37-15-16-38-14-12-30-25(33)23(39-18-7-3-1-4-8-18)24(26(30)34)40-19-9-5-2-6-10-19/h1-10,20H,11-17H2,(H2,28,31)(H,29,32)(H,35,36)/t20-/m0/s1
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| InChIKey |
PDFHOSUQGZQUDM-FQEVSTJZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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587.676
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Polar area
|
165.33
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Complexity
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1123.614127
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xlogp Value
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2.0195
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Heavy Count
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40
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Rot Bonds
|
17
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Hbond acc
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9
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker