Linker Information
General Information of This Linker
| Linker ID |
LIN0EVGEF
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| Linker Name |
TWI857167B-IC-108-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C16H18F4O10S
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| Isosmiles |
O=C(OC1=C(F)C(F)=C(S(=O)(O)=O)C(F)=C1F)CCOCCOCCOCCC(O)=O
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| InChI |
InChI=1S/C16H18F4O10S/c17-11-13(19)16(31(24,25)26)14(20)12(18)15(11)30-10(23)2-4-28-6-8-29-7-5-27-3-1-9(21)22/h1-8H2,(H,21,22)(H,24,25,26)
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| InChIKey |
NTYIVNYJYSKGGS-UHFFFAOYSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
478.369
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Polar area
|
145.66
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Complexity
|
813.5098842
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xlogp Value
|
1.3097
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Heavy Count
|
31
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Rot Bonds
|
14
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Hbond acc
|
8
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Hbond Donor
|
2
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Each Antibody-drug Conjugate Related to This Linker