Linker Information
General Information of This Linker
| Linker ID |
LIN0EROPQ
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| Linker Name |
T-9 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C24H31N3O15S
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| Isosmiles |
O=S(O)(OC1=C(O[C@H]2[C@H](O)[C@@H](O)[C@@H](O)[C@H](O2)CO)C=CC(C(NCCOCCNC(CCN3C(C=CC3=O)=O)=O)=O)=C1)=O
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| InChI |
InChI=1S/C24H31N3O15S/c28-12-16-20(32)21(33)22(34)24(41-16)40-14-2-1-13(11-15(14)42-43(36,37)38)23(35)26-7-10-39-9-6-25-17(29)5-8-27-18(30)3-4-19(27)31/h1-4,11,16,20-22,24,28,32-34H,5-10,12H2,(H,25,29)(H,26,35)(H,36,37,38)/t16-,20+,21+,22-,24-/m1/s1
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| InChIKey |
FWGBGBYBXHMSQT-IZIQSIKJSA-N
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| Pharmaceutical Properties |
Molecule Weight
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633.585
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Polar area
|
267.79
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Complexity
|
1240.854049
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xlogp Value
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-3.7754
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Heavy Count
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43
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Rot Bonds
|
15
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Hbond acc
|
14
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker