Linker Information
General Information of This Linker
| Linker ID |
LIN0ERFCU
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| Linker Name |
CN119317630A ADC-C12 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H39N5O16
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| Isosmiles |
CC([C@H](NC(CCNC(CNC(CCC(O)=O)=O)=O)=O)C(N[C@@H](CO[C@H]1[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O1)C(NCC(O)=O)=O)=O)C
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| InChI |
InChI=1S/C25H39N5O16/c1-10(2)17(30-13(32)5-6-26-14(33)7-27-12(31)3-4-15(34)35)23(42)29-11(22(41)28-8-16(36)37)9-45-25-20(40)18(38)19(39)21(46-25)24(43)44/h10-11,17-21,25,38-40H,3-9H2,1-2H3,(H,26,33)(H,27,31)(H,28,41)(H,29,42)(H,30,32)(H,34,35)(H,36,37)(H,43,44)/t11-,17-,18-,19-,20+,21-,25+/m0/s1
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| InChIKey |
LNYFDAKMEGEXSX-OVXCBRJZSA-N
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| Pharmaceutical Properties |
Molecule Weight
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665.606
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Polar area
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336.55
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Complexity
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1071.317538
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xlogp Value
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-5.7911
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Heavy Count
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46
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Rot Bonds
|
19
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Hbond acc
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13
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Hbond Donor
|
11
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Each Antibody-drug Conjugate Related to This Linker