Linker Information
General Information of This Linker
| Linker ID |
LIN0EOLOT
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| Linker Name |
T-125 linker
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| Linker Type |
Beta-glucuronide based linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C28H35N5O13
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| Isosmiles |
CN(CCOCCN1C=C(N=N1)CCOCCN(C(C=C2)=O)C2=O)C(C3=CC=C(O[C@H]4[C@H](O)[C@@H](O)[C@H](O)[C@H](O4)C(O)=O)C(O)=C3)=O
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| InChI |
InChI=1S/C28H35N5O13/c1-31(7-11-44-12-8-32-15-17(29-30-32)6-10-43-13-9-33-20(35)4-5-21(33)36)26(40)16-2-3-19(18(34)14-16)45-28-24(39)22(37)23(38)25(46-28)27(41)42/h2-5,14-15,22-25,28,34,37-39H,6-13H2,1H3,(H,41,42)/t22-,23-,24+,25-,28+/m0/s1
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| InChIKey |
WTJQFSBPLQPNQE-CPIYQPHESA-N
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| Pharmaceutical Properties |
Molecule Weight
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649.61
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Polar area
|
243.54
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Complexity
|
1354.383644
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xlogp Value
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-2.4724
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Heavy Count
|
46
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Rot Bonds
|
16
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Hbond acc
|
15
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker