Linker Information
General Information of This Linker
| Linker ID |
LIN0EMLOH
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| Linker Name |
CN113549127A-ADC-23-linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C25H41N7O9S
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| Isosmiles |
NCCCC[C@H](NC(COCC(NCCOCCOCCNC(CCCNC(C1=CN=C(S)N=C1)=O)=O)=O)=O)C(O)=O
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| InChI |
InChI=1S/C25H41N7O9S/c26-6-2-1-4-19(24(37)38)32-22(35)17-41-16-21(34)28-9-11-40-13-12-39-10-8-27-20(33)5-3-7-29-23(36)18-14-30-25(42)31-15-18/h14-15,19H,1-13,16-17,26H2,(H,27,33)(H,28,34)(H,29,36)(H,32,35)(H,37,38)(H,30,31,42)/t19-/m0/s1
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| InChIKey |
BPPCOJHCDJPHJD-IBGZPJMESA-N
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| Pharmaceutical Properties |
Molecule Weight
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615.71
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Polar area
|
233.19
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Complexity
|
907.8616306
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xlogp Value
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-1.7441
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Heavy Count
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42
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Rot Bonds
|
24
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Hbond acc
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12
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Hbond Donor
|
7
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Each Antibody-drug Conjugate Related to This Linker