Linker Information
General Information of This Linker
| Linker ID |
LIN0EJYXZ
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| Linker Name |
CN119317630A ADC-C8 Linker
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C23H34N4O14
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| Isosmiles |
CC([C@H](NC(CCNC(CN1C(CCC1=O)=O)=O)=O)C(N[C@@H](CO[C@H]2[C@H](O)[C@@H](O)[C@H](O)[C@@H](C(O)=O)O2)C(O)=O)=O)C
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| InChI |
InChI=1S/C23H34N4O14/c1-9(2)15(26-11(28)5-6-24-12(29)7-27-13(30)3-4-14(27)31)20(35)25-10(21(36)37)8-40-23-18(34)16(32)17(33)19(41-23)22(38)39/h9-10,15-19,23,32-34H,3-8H2,1-2H3,(H,24,29)(H,25,35)(H,26,28)(H,36,37)(H,38,39)/t10-,15-,16-,17-,18+,19-,23+/m0/s1
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| InChIKey |
NLSATLBRNZYFJE-QRQUDWBBSA-N
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| Pharmaceutical Properties |
Molecule Weight
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590.539
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Polar area
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278.43
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Complexity
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965.5084952
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xlogp Value
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-4.7393
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Heavy Count
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41
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Rot Bonds
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14
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Hbond acc
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12
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Hbond Donor
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8
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Each Antibody-drug Conjugate Related to This Linker