Linker Information
General Information of This Linker
| Linker ID |
LIN0EGWCP
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|---|---|---|---|---|---|---|
| Linker Name |
TW202506738A-C-093-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H58N4O15
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| Isosmiles |
COCCOCCOCCOCCOCCOCCOCCOCCNC(CC[C@H](NC(CCCN1C(C=CC1=O)=O)=O)C(NCCCC(O)=O)=O)=O
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| InChI |
InChI=1S/C34H58N4O15/c1-46-14-15-48-18-19-50-22-23-52-26-27-53-25-24-51-21-20-49-17-16-47-13-11-35-29(39)7-6-28(34(45)36-10-2-5-33(43)44)37-30(40)4-3-12-38-31(41)8-9-32(38)42/h8-9,28H,2-7,10-27H2,1H3,(H,35,39)(H,36,45)(H,37,40)(H,43,44)/t28-/m0/s1
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| InChIKey |
ZYYZFNPCJFARIB-NDEPHWFRSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
762.851
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Polar area
|
235.82
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Complexity
|
996.6385288
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xlogp Value
|
-1.1836
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Heavy Count
|
53
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Rot Bonds
|
37
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Hbond acc
|
14
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Hbond Donor
|
4
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Each Antibody-drug Conjugate Related to This Linker