Linker Information
General Information of This Linker
| Linker ID |
LIN0EFVWB
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| Linker Name |
CN119630431A-ADC-22-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C34H35N3O8S2
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| Isosmiles |
O=C(N1CCOCCOCCC(N[C@@H](CC2=CC=CC=C2)C(NCC(O)=O)=O)=O)C(SC3=CC=CC=C3)=C(SC4=CC=CC=C4)C1=O
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| InChI |
InChI=1S/C34H35N3O8S2/c38-28(36-27(32(41)35-23-29(39)40)22-24-10-4-1-5-11-24)16-18-44-20-21-45-19-17-37-33(42)30(46-25-12-6-2-7-13-25)31(34(37)43)47-26-14-8-3-9-15-26/h1-15,27H,16-23H2,(H,35,41)(H,36,38)(H,39,40)/t27-/m0/s1
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| InChIKey |
GWTXKSXUDOHPBE-MHZLTWQESA-N
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| Pharmaceutical Properties |
Molecule Weight
|
677.801
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Polar area
|
151.34
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Complexity
|
1434.477522
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xlogp Value
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3.503
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Heavy Count
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47
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Rot Bonds
|
19
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Hbond acc
|
9
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Hbond Donor
|
3
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Each Antibody-drug Conjugate Related to This Linker