General Information of This Linker
Linker ID
LIN0EDPXW
Linker Name
Mcc-hydrazide
Linker Type
Flexible dual-reactive (thiol) linker
Antibody-Linker Relation
Uncleavable
Structure
Formula
C12H17N3O3
Isosmiles
NNC(=O)C1CCC(CN2C(=O)C=CC2=O)CC1
InChI
InChI=1S/C12H17N3O3/c13-14-12(18)9-3-1-8(2-4-9)7-15-10(16)5-6-11(15)17/h5-6,8-9H,1-4,7,13H2,(H,14,18)
InChIKey
BYLZUECTWAELHO-UHFFFAOYSA-N
Pharmaceutical Properties
Molecule Weight
251.286
Polar area
92.5
Complexity
18
xlogp Value
-0.2923
Heavy Count
18
Rot Bonds
3
Hbond acc
4
Hbond Donor
2
Each Antibody-drug Conjugate Related to This Linker