Linker Information
General Information of This Linker
| Linker ID |
LIN0EALNG
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| Linker Name |
TW202506738A-C-087-LINKER
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| Linker Type |
Cathepsin-cleavable linker
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| Antibody-Linker Relation |
Cleavable
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| Structure |
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| Formula |
C32H54N6O16
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| Isosmiles |
CCOC(NCCNC(CCCNC([C@@H](NC(CCCN1C(C=CC1=O)=O)=O)CCC(NCCOCOCOCOCOCOCOCOC)=O)=O)=O)=O
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| InChI |
InChI=1S/C32H54N6O16/c1-3-54-32(45)36-14-13-33-26(39)6-4-12-35-31(44)25(37-28(41)7-5-16-38-29(42)10-11-30(38)43)8-9-27(40)34-15-17-47-19-49-21-51-23-53-24-52-22-50-20-48-18-46-2/h10-11,25H,3-9,12-24H2,1-2H3,(H,33,39)(H,34,40)(H,35,44)(H,36,45)(H,37,41)/t25-/m0/s1
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| InChIKey |
OUPRXLQHTTWRAG-VWLOTQADSA-N
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| Pharmaceutical Properties |
Molecule Weight
|
778.81
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Polar area
|
265.95
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Complexity
|
1071.072168
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xlogp Value
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-1.7034
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Heavy Count
|
54
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Rot Bonds
|
34
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Hbond acc
|
16
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Hbond Donor
|
5
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Each Antibody-drug Conjugate Related to This Linker